Description
Our Mission:
Dash accelerates drug development. By fusing advanced automation-native lab workflows and integrated software into a unified platform, we provide the biopharma industry with the high-velocity, high-quality, data-driven development solutions required to get life-saving therapies to patients faster. Dash seeks to continuously improve industry KPIs and materially reduce the time and cost to bring a drug to market.
Company Summary:
Dash Bio is building the operating system for modern drug development. We are moving beyond the manual, fragmented processes of traditional service providers by taking a technology-first approach to bioanalysis. Our platform is tech-enabled, automated, and GLP-compliant with the goal to industrialize the scientific workflows that act as bottlenecks in the industry. We deliver next-generation clinical bioanalysis results with unprecedented speed and precision.
We are a team of builders operating at the intersection of biology, hardware, and code. This is an environment for scientists and engineers who are tired of the status quo and are ready to apply their skills to solve hard problems at scale. We don't just run assays, we architect the systems that will define the future of drug development.
We are a place where employees are stretched to do the best work of their career. We are looking for engineers, scientists, and biotechnicians who want to make an impact on the world and leverage their skills in an innovative way.
Role Description:
We are seeking a highly motivated scientist with bioanalytical LC/MS expertise to join our dynamic team. The ideal candidate will leverage their deep background in bioanalytical development to design cutting edge assays that integrate with Dash’s software and robotics platform. The successful candidate will drive projects from concept through completion, mentor junior staff, ensure adherence to regulatory standards, and deliver exceptional results in a fast-paced, innovation-driven environment.
Key Responsibilities:
Method Development & Lab Operations: Design, develop, and implement quantitative LC/MS bioanalytical assays for various therapeutic modalities including small molecules, oligonucleotides, and proteins.
Workflow Optimization: Select appropriate workflows for sample preparation, including protein precipitation (PPT), LLE, SPE, immuno-capture and drive their development on high-throughput automated platforms.
Experimental Design: Drive experimental design and validation efforts for LC/MS assays to enhance sensitivity, specificity, throughput, and cost-effectiveness.
Hands-on Instrumentation: Operate, maintain, and troubleshoot SCIEX QqQ and Thermo Orbitrap instrumentation. Evaluate and implement new analytical equipment, software, and instrumentation to further enhance lab capabilities and throughput.
Data Analysis & Documentation: Utilize statistical and analytical tools to process and interpret complex LC/MS datasets. Author high-quality study reports, SOPs, analytical methods. Clearly communicate findings to internal teams and external clients, converting complex data into actionable insights that shape project strategies and regulatory submissions.
Project Leadership: Manage multiple LC/MS-centric projects simultaneously, maintaining strict timelines, quality compliance, and alignment with client and regulatory requirements. Mentor and train junior scientists and technicians, providing hands-on guidance in assay setup, method transfer, data interpretation, and adherence to SOPs.
Client Collaboration: Partner closely with clients to define LC/MS assay requirements, experimental designs, timelines, and deliverables. Provide timely updates, data-driven reports, and presentations that meet or exceed client expectations.
Qualifications:
Education & Experience: Ph.D. in Biochemistry, Chemistry, Chemical Engineering, or a related field with 1-2 years of industry or post-doctoral experience, or M.S. with 5+ years of relevant experience.
Technical Expertise: Demonstrated expertise in LC/MS method development, validation, and troubleshooting.
Regulatory Knowledge: Experience developing and validating assays in a GxP environment preferred.
Project Management: Strong project management skills with the ability to lead and perform in multidisciplinary teams.
Soft Skills: Excellent communication, interpersonal, and problem-solving abilities, with acute attention to detail.
What We Offer:
The chance to work at the cutting edge of bioanalytical innovation, where LC/MS plays a central role.
A collaborative and inclusive culture that fosters professional growth, learning, and knowledge sharing.
A competitive salary and comprehensive benefits package.
